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Quintessence Publishing: Journals: QI
Quintessence International

Edited by Eli Eliav

ISSN 0033-6572 (print) • ISSN 1936-7163 (online)

July 1999
Volume 30 , Issue 7

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New clinical index for drug-induced gingival overgrowth

Eva InglÚs, DDS, MS/Jeffrey A. Rossmann, DDS, MS/Raul G. Caffesse, DDS, MS, Dr Odont, Drhc

Pages: 467-473
PMID: 10635259

The numbers of patients using medications that induce gingival overgrowth are expanding rapidly. The tremendous increase in the number of organ transplants being performed, each requiring treatment with the immunosuppressive drug of choice, cyclosporine, has created a new dilemma in management of the gingival tissues. Additionally, cyclosporine-induced hypertension is frequently treated with calcium channel blockers, such as nifedipine, both drugs acting synergistically to induce gingival overgrowth. At present, the profession lacks a well-defined and easy-to-use clinical index for classifying overgrown gingival tissue. This article describes a comprehensive, yet simple, scoring system for enlarged tissues that may provide direction to the clinician and standardize evaluation. This system may also give guidance for the most appropriate time for surgical treatment of drug-induced gingival overgrowth.

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