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Quintessence Publishing: Journals: QI
Quintessence International

Edited by Eli Eliav

ISSN 0033-6572 (print) • ISSN 1936-7163 (online)

February 2007
Volume 38 , Issue 2

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Plasmablastic lymphoma: A case report

Gaoussou Toure, MD, PhD / Anne-Marie Roucayrol, MD / Jean Paul Meningaud, MD, PhD / Jacques-Charles Bertrand, MD

Pages: 161–163
PMID: 17263156

Plasmablastic lymphoma is a rare subcategory of non-Hodgkin lymphoma frequently associated with human immunodeficiency virus. It is a large B-cell lymphoma that has a predilection for the oral cavity. Clinically, plasmablastic lymphoma may mislead to a diagnosis of Kaposi’s sarcoma. When infected, plasmablastic lymphoma may mimic an odontogenic cellulitis. Epstein-Barr virus and human herpesvirus 8 are very often associated. Awareness of this entity can prevent misdiagnosis with nonlymphoid malignancies, notably Kaposi’s sarcoma, because this lesion does not express the conventional B-cell markers. Unfortunately, as for other high-grade lymphomas in patients with acquired immunodeficiency syndrome (AIDS), the prognosis is poor. The case of a heterosexual 42-year-old man referred for a right hemifacial neoplasm is reported. (Quintessence Int 2007;38:161–163)

Key words: Epstein-Barr virus, human herpesvirus 8, human immunodeficiency virus (HIV), non-Hodgkin lymphoma, plasmablastic lymphoma, oral cavity

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