Follow Us      

LOGIN

   Offical Journal of The Academy of Osseointegration

 
Share Page:
Back

Volume 19 , Issue 3
May/June 1999

Pages 259-257


GBR in Human Extraction Sockets and Ridge Defects Prior to Implant Placement: Clinical Results and Histologic Evidence of Osteoblastic and Osteoclastic Activities in DFDBA

Federico Brugnami, DDS/Peter R. Then, DMD/Hidetada Moroi, DMD/Sadrudin Kabani, DMD, MS/Cataldo W. Leone, DMD, DMSc


PMID: 10635172
DOI: 10.11607/prd.00.0316

This study evaluated new bone formation in 3 types of osseous defects following treatment with demineralized freeze-dried bone allografts (DFDBA) and cell-occlusive membranes. For 8 patients electing to receive implant treatment, a distinction was made among 3 clinical situations: (1) existing alveolar ridge defects; (2) extraction sockets with lost buccal plate; and (3) extraction sockets with an intact alveolus. Implants were placed a mean of 6 months after the regenerative procedure. Clinical examination of bone width and height at the time of implant placement showed sufficient augmentation or preservation, and implants were inserted without incident. Histologic examination of hard tissue biopsies obtained from the implant sites revealed no discernible differences among the 3 types of defects. Specifically, all sites demonstrated DFDBA particles surrounded by woven or lamellar bone. No fibrous encapsulation of DFDBA or inflammatory reaction was observed. Osteoblasts were found lining marrow spaces. Howeship’s lacunae, with and without resident osteoclasts, were clearly seen in several DFDBA particles; this finding supports the belief that DFDBA undergoes osteoclasis in vivo. These results demonstrate that commercially available DFDBA has osteoconductive properties that lead to appositional new bone growth in both self-contained and non–self contained osseous defects.


Full Text PDF File | Order Article

 

 
Get Adobe Reader
Adobe Acrobat Reader is required to view PDF files. This is a free program available from the Adobe web site.
Follow the download directions on the Adobe web site to get your copy of Adobe Acrobat Reader.

 

© 2020 Quintessence Publishing Co, Inc

PRD Home
Current Issue
Ahead of Print
Archive
Author Guidelines
About
Submission Form
Submit
Reprints
Permission
Advertising
Quintessence Home
Terms of Use
Privacy Policy
About Us
Contact Us
Help