Share Page:

Volume 34 , Issue 6
November/December 2019

Pages 14131422

Comparative Histomorphometric Evaluation of Bone Regeneration with Different Preparations of Xenogeneic Tooth Block Bone

Yong-Suk Moon, MS/Dong-Seok Sohn, DDS, PhD/Grace Kim, BDS/Insook Park, DDS, PhD

PMID: 31711083
DOI: 10.11607/jomi.7290

Purpose: The aim of this animal study was to evaluate new bone formation in human dentin block grafted on rabbit calvaria according to a comparison of histologic analysis. Materials and Methods: Human teeth were prepared according to four different types of dentin blocks: group 1, demineralized and microperforated dentin block; group 2, demineralized dentin block; group 3, undemineralized and microperforated dentin block; group 4, undemineralized dentin block. These four different dentin blocks were grafted on nine rabbit calvaria, and animals were sacrificed at 2, 4, and 8 weeks after the surgical procedure for histologic evaluation. Results: In group 1, histologically, new bone formation was initiated at the interface between demineralized and microperforated dentin block and host bone and microholes at 2 weeks, and mature bone was observed at 8 weeks. In group 3, new bone formation was observed at 8 weeks in the undemineralized and microperforated dentin block bottom and microholes. The bone formation ratio of group 1 was significantly higher at 2, 4, and 8 weeks compared with groups 2, 3, and 4 (P < .05). The bone formation ratio in microholes at 2 and 8 weeks in group 1 was significantly greater than in group 3 (P < .05). Conclusion: New bone formation of the demineralized dentin block began more rapidly than the undemineralized dentin block, and perforated dentin block was more effective in bone formation than dentin block without microholes.

Full Text PDF File | Order Article


Get Adobe Reader
Adobe Acrobat Reader is required to view PDF files. This is a free program available from the Adobe web site.
Follow the download directions on the Adobe web site to get your copy of Adobe Acrobat Reader.


© 2020 Quintessence Publishing Co, Inc JOMI Home
Current Issue
Ahead of Print
Author Guidelines
Accepted Manuscripts
Submission Form
Quintessence Home
Terms of Use
Privacy Policy
About Us
Contact Us